Cambridge Healthtech Institute’s Inaugural

Internet of Diagnostic Things

Connected Diagnostics: IoT, Sensors, Wearables, and Smartphones Bring Point-of-Care Testing to the Patient

June 17, 2019

The latest advances in biosensors, wearables, Internet of Medical Things, and smartphone capabilities are promising to revolutionize healthcare and drug development by shifting point-of-care diagnostics to the patient, offering novel digital biomarkers for innovating clinical trials, and enabling the next generation of patient-centric personalized medicine. CHI's Inaugural Internet of Diagnostic Things symposium will present the latest advances in connected diagnostics, including connected biosensors, wearables and implantables, smartphone-enabled diagnostics, remote patient monitoring, and digital biomarkers.

Final Agenda

Monday, June 17

8:30 am Registration Open and Morning Coffee

Waterfront 1

9:00 Welcome and Opening Remarks

Christopher M. Hartshorn, PhD, Program Director, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health

9:10 Towards Smart and Connected Point of Care Molecular Diagnostics of Infectious Diseases

Liu_ChangchunChangchun Liu, PhD, Associate Professor, Biomedical Engineering Department, University of Connecticut

Smartphones have a growing and pervasive influence on our daily life. Especially with the rapid development of microfluidics technology, the incorporation of microfluidics technology with smartphone-based detection technology will create a new paradigm shift towards affordable, smart and connected health monitoring. In this talk, I will introduce our molecular diagnostic chips, smart connected devices and their applications in cervical cancer screening and infectious disease detection at the point of care.

9:40 Portability and Security for the Next Generation Point-of-Care Diagnostics

Temiz_YukselYuksel Temiz, PhD, Research Staff Member, IBM Research-Zurich

Diagnostic technologies based on microfluidics and IoT represent a strong opportunity for providing sensitive, low-cost, rapid and connected diagnostics at the point-of-care. In this presentation, I will share our vision on a portable and connected diagnostic platform, which uses capillary-driven microfluidics and compact peripherals enabling communication with a smartphone. I will also discuss our recent efforts on the development of security features that can protect diagnostic tests from counterfeiting.

10:10 Using AI to Enable IoT and Diagnostics Devices to Deliver Personalized Care at Global Scale

Shih_TingTing Shih, MBA, MS, CEO & Founder, ClickMedix

Technological advances made possible rapid emergence of point-of-care devices. However, at scale, each device needs to work within healthcare workflows, policies, and clinical guidelines to improve the health of patients. Having worked in more than 20 countries, in this talk, Ting Shih will go over an end-to-end roadmap for deploying IoT devices, integrated with clinical protocols, personalized care plans, and payment schemes to maximize the impact of IoTs and demonstrate improvement on patient health outcomes. With the use of AI, the impact of IoTs can be magnified throughout patient populations.

10:40 Networking Coffee Break


11:10 Wearables, Ingestibles, Invisibles - New Diagnostic Platforms Enabled by Silicon and AI

Van_Hoof_ChrisChris Van Hoof, PhD, Senior Director, Connected Health Solutions, Imec

How are highly-sensitive, AI-powered, clinical-grade diagnostics and wearables being used for early disease detection, personalized treatment and prevention? Find out how our wearable health patches can serve the field of nephrology. How fast eye tracking glasses play a role in neurodegenerative disease management. How ingestible sensors monitor gastrointestinal disorders. And how wearable sensors assist the psychiatrist. These tech and AI innovations kickstarted a health tech revolution.

REPLY_valorem 12:10 pm IoT, AI, and Digital Twins in Healthcare Operations

Evans_ShawnShawn Evans, Director, Edge Technologies, Valorem Reply

In this session, we’ll discuss real-world cases where emerging technologies such as IoT, AI, and Digital Twins are bringing transformational changes to healthcare operations. We’ll explore how device telemetry, when combined with AI, can make powerful forecasts and analysis for operational efficiency, bottom line impact and transformational outcomes. We’ll also discuss Digital Twins and innovative ways to visualize data to increase access to real-time information across your organization despite geographic barriers.

12:40 Enjoy Lunch on Your Own

1:10 Session Break



1:55 Piloting a Living Lab for Evaluation and Development of Novel Digital Biomarkers

Richards_StevenSteven Richards, PharmD, Investigator, Biomarker Development, Novartis Institutes for BioMedical Research

The incorporation of digital biomarkers in clinical trials offers the possibility of replacing poor endpoints with more sensitive measures, while lowering cost and patient burden. Prior to implementing new technologies in clinical trials, it is important to conduct feasibility studies in realistic deployment environments. Living laboratories are simulated real-world environments equipped with embedded sensors, which allow us to establish ecological validity of digital biomarkers measured at-home.

2:25 Solving the ‘Last Mile’ Problem in the Delivery of Cancer Care: Cyber-Physical Systems and Smart Connected Health to Support Clinical Decision Making

Hartshorn_ChristopherChristopher M. Hartshorn, PhD, Program Director, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health

Cancer patients disconnected from resource intensive cancer centers face challenges beyond simply the disease they are dealing with. This ‘last mile’ problem of healthcare delivery is becoming more tractable with modern broadband connectivity and sensors. This talk will discuss major barriers from the patient and clinical workflow/integration sides as well as synergistic efforts across NCI and other agencies attempting to enable these tools for clinical applications and decision support.

2:55 Networking Refreshment Break

3:15 PANEL DISCUSSION: Future of Connected Diagnostics

Hartshorn_ChristopherModerator: Christopher M. Hartshorn, PhD, Program Director, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health


Ting Shih, MBA, MS, CEO & Founder, ClickMedix

Yuksel Temiz, PhD, Research Staff Member, IBM Research-Zurich

Wasim Q. Malik, PhD, Managing Partner, Iaso Ventures; Director, Massachusetts General Hospital, Harvard Medical School

Discussion topics include:

  • What are the emerging applications of IoT in diagnostics and remote patient monitoring?
  • What is needed for patient compliance and increased adoption?
  • What IT capabilities are needed for “big data” analysis? Opportunities for AI and machine learning?
  • How can this technology benefit big pharma? Applications in clinical trials, patient engagement, and digital therapeutics?
  • How can connected diagnostics serve as digital biomarkers in clinical trials?

4:45 Close of Symposium

5:00 Dinner Short Course Registration

5:30 Dinner Short Course*

*Separate registration required.

Stay on to attend Tuesday, June 18 - Wednesday, June 19

Digital Health: Pharmaceutical Executive Summit

Wednesday, June 19 - Thursday, June 20

Digital Biomarkers: Biosensors, Wearables and mHealth