Cambridge Healthtech Institute’s 5th Annual

3D Cellular Models

Engineering Predictive Preclinical Screening Models

June 18-19, 2019


Inadequate representation of the human tissue environment during a preclinical screen can result in inaccurate predictions of a drug candidate’s effects. Thus, pharmaceutical investigators are searching for preclinical models that closely resemble original tissue for predicting clinical outcome. Three-dimensional cell culture recapitulates normal and pathological tissue architectures that provide physiologically relevant models to study normal development and disease. However, challenges remain for high-throughput screening as researchers must procure large numbers of identical 3D cell cultures, develop assays and obtain fast, automated readouts from these more complex assays. Join cell biologists, tissue engineers, assay developers, screening managers and drug developers at Cambridge Healthtech Institute’s 5th Annual 3D Cellular Models conference as they discuss strategies that accelerate the identification of novel therapeutic leads.

MODELING COMPLEX DISEASES TO IDENTIFY NOVEL THERAPIES

Blood-Brain-Barrier Organoids for Modeling the Permeability of CNS Therapeutics

Choi-Fong Cho, PhD, Instructor, Department of Neurosurgery, Brigham and Women’s Hospital, Harvard Medical School

Talk Title to Be Announced

Graham Marsh, PhD, Scientist, Biogen

Engineering of 3-Dimensional Brain-Like Tissues to Study Neurological Disorders

Thomas Nieland, PhD, Research Associate Professor, Initiative for Neural Science, Disease & Engineering (INSciDE@Tufts), Department of Biomedical Engineering, Tufts University

Contracting Muscle Models in a Dish for Physiological Drug Screening

Hansjoerg Keller, PhD, Senior Investigator I, Musculoskeletal, Novartis Institutes for BioMedical Research

Physiologically Based Pharmacokinetic and Pharmacodynamic Analysis Enabled by Microfluidically Linked Organs-on-Chips

Rachelle Prantil-Baun, PhD, Senior Staff Scientist, Wyss Institute

FOCUS ON ECM: BIOPRINTING AND FUNCTIONALIZATION

Putting 3D Bioprinting to the Use of Tissue Model Fabrication

Yu Shrike Zhang, PhD, Research Faculty & Associate Bioengineer, Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School & Harvard-MIT Division of Health Sciences and Technology

CO-PRESENTATION: Engineering Reproduction: Microfluidic and Tissue Engineering Approaches for Female Fertility

Emma S. Gargus, MD/PhD Candidate, Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University

Hunter B. Rogers, PhD Candidate, Ob/Gyn, Feinberg School of Medicine, Northwestern University

Chemoselective Functionalization of Native Biomaterials for 3D Tissue Engineering

Xi Ren (Charlie), Assistant Professor, Biomedical Engineering, Carnegie Mellon University

3D Bio-Printed Vascularized Glioblastoma Model for Drug Discovery

Guohao Dai, PhD, Associate Professor, Department of Bioengineering, Northeastern University

AT THE INTERFACE OF ENGINEERING AND RESPIRATORY MEDICINE: UPDATES AND APPLICATIONS

Fibrotic Microtissue Array to Predict Anti-Fibrosis Drug Efficacy

Ruogang Zhao, PhD, Assistant Professor of Biomedical Engineering, Department of Biomedical Engineering, State University of New York at Buffalo 

Modeling Human Airway Diseases in Three Dimension: Introducing Small Airway-on-a-Chip and Breathing-Smoking Lung-on-a-Chip Microfluidic Technologies

Kambez H. Benam, PhD, Assistant Professor, Division of Pulmonary Sciences and Critical Care Medicine, Departments of Medicine & Bioengineering, University of Colorado

 


For more details on the conference, please contact:
Mana Chandhok
Conference Producer
Phone: 781-972-1350
Cambridge Healthtech Institute
Email: mchandhok@healthtech.com

For partnering and sponsorship information, please contact:


Companies A-K
Rod Eymael
Business Development Manager
Cambridge Healthtech Institute
Phone: 781-247-6286
Email: reymael@healthtech.com

Companies L-Z
Joseph Vacca, M.S.
Director, Business Development
Cambridge Healthtech Institute
Phone: 781-972-5431
Email: jvacca@healthtech.com