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Week of 10.1.08

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Neil W Gibson of OSI Pharmaceuticals

Jeffrey Settleman Harvard Medical School and MGH Cancer Center

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  THIS WEEK
 

FEATURE:

Prolong Pharmaceuticals – PEGged For Success?
By Alissa Poh

TOct. 1, 2008 | In Britain, people often use the phrase “pegging away” to describe working hard at something.

Across the pond, in New Jersey, the folks at Prolong Pharmaceuticals are also pegging away, attaching polyethylene glycol (PEG) to a variety of protein-based drugs. Or, to use the proper term, “pegylating” these drugs to improve pharmacokinetics, extend circulation time and decrease toxicity, all of which make for enhanced therapeutic effects. 

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